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Risk Estimates - Work package 3


Work package leader: Sarah Darby


Objectives. Calculate risk of cardio-vascular disorders in women previously diagnosed with breast cancer.


Description of work. The statistical analyses of the data will be performed in Oxford. The construction of the dosimetric estimates will also be carried out in Oxford and appropriate dose and epidemiologic information will be integrated. The data will be analysed using standard statistical methods and the computer package STATA where appropriate, although where appropriate new statistical methodology will be developed (e.g. to take account of uncertainties in the dose estimates) and appropriate bespoke programs prepared. It is envisaged that the results will lead to an estimated dose-response relationship for the relationship between cardiac dose and subsequent risk of cardiovascular disease.


















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