to Karolinska Institutet

Oxford University

The chief aims of the Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU) are to generate, and to disseminate, reliable evidence about widely practicable methods of prevention and treatment of vascular, neoplastic and other chronic diseases, which account in many populations for most of the premature mortality, for much of the disability, and for much of the medical impairment of the quality of life.

The CTSU has around 150 staff, including expertise on both cancer and cardiovascular disease. It also has substantial experience in the statistical analysis of epidemiological studies such as this, and in communicating the results of such studies both to health care professionals and to the general public.

Project Staff

Professor Sarah Darby works in the CTSU with personal funding from Cancer Research UK. She is an internationally recognized investigator in the field of radiation and cancer epidemiology and is also a member of the Secretariat of the Early Breast Cancer Trialists‘ Collaborative Group. She has published over 180 scientific papers and has been consultant to the United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) and the International Agency for Research on Cancer (IARC). She presently participates in the European Commission study aimed at estimating the risk of lung cancer arising from residential radon.

Dr Paul McGale works in the CTSU, University of Oxford, supported by funding from Cancer Research UK. After gaining a doctorate in astronomy he has 20 years experience as a computer programmer and recently has completed an MSc in Medical Statistics at the London School of Hygiene and Tropical Medicine. He has published 20 scientific papers and is a member of the Secretariat of the Early Breast Cancer Trialists' Collaborative Group with responsibility for running the statistical analyses for the trials of local therapies.

Dr Carolyn Taylor is a specialist registrar in clinical oncology with a special interest in the dosimetric aspects of breast cancer radiotherapy. She is intending to join the CTSU for the duration of this project and to use the dosimetric aspects of the project as the basis for her scientific doctorate.

















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